Scientists have made history after successfully creating seven mice with two fathers, a breakthrough hailed as "revolutionary" by experts. The research, published Wednesday, used a technique to produce eggs from the cells of two male mice, and then used those eggs in a surrogate mother to give birth to the seven mice. The team of scientists, led by Dr. Liuhua Jiang of Shanghai's Institute of Neuroscience, said the proof-of-concept experiment marks a major milestone in reproductive biology. "This is a remarkable achievement that opens up a new field of research," said Dr. Jiang. "It provides a proof of concept that two males can produce offspring, and it has implications for reproductive biology in general." The scientists said the low success rate of the experiment, along with adaptation concerns and ethical considerations, means the technique is still a long way from being used in humans. However, the breakthrough raises the prospect of a variety of new reproductive possibilities, including the creation of offspring from two same-sex parents, or even from three parents. "This is a very exciting development," said Dr. Michael Sherman, a reproductive biologist at the University of California, San Francisco. "It's a major step forward in understanding how reproduction works, and how we might be able to manipulate it in the future."